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| Information about Ionamine |
 Ionamine - IONAMIN® (phentermine hydrochloride) is set in a resin matrix compound and is manufactured by Celltech Pharmaceuticals / Medeva Pharmaceuticals. The resin compound allows the phentermine to release slowly into the system, but is not time released per se. Some patients like it because they have fewer side effects. It is the only fentermine resin on the market; there are no generics. It comes in 30 mg and 15 mg capsules. The 15 mg capsule is gray and yellow, the 30 mg capsule is all yellow. Each capsule is labeled "Ionamin and the mg strength." or "Ionamin"
Ionamine is a sympathomimetic amine with pharmacologic activity similar to the prototype drug of this class used in obesity, amphetamine (d- and df-amphetamine). Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for.
Drugs of this class used in obesity are commonly known as "anorectics" or "anorexigenics." It has not been established, however, that the action of such drugs in treating obesity is primarily one of appetite suppression. other central nervous system actions, or metabolic effects may be involved.
Adult obese subjects instructed in dietary management and treated with "anorectic" drugs, lose more weight on the average than those treated with placebo and diet, as determined in relatively short-term clinical trials.
IONAMINE Capsules are indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for patients with an initial body mass index >=30 kg/m2, or >=27 kg/m2 in the presence of other risk factors (e.g., hypertension, diabetes, hyperlipidemia). |
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Ionamine
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